Drugstore Supply Channel of Bangladesh and Other Countries of the World Essay Example for Free

Drugstore Supply Channel of Bangladesh and Other Countries of the World Essay The pharmaceutical industry of Bangladesh is at a matured stage with strong companies like Square, Beximco, Incepta etc. Drug stores have emerged in a good amount as well. Lazz Pharma once was the only good place to buy medicines which is not the current condition of the market. This is mostly because of the new technological additions to maintain an effective supply chain in the business. As the market got developed, competition rose as well. Hence, companies tried to adapt new technologies and advancement to hold a stronger position than their competitors. In addition, most of the intermediaries in the channel are owned by the companies. Therefore, the control is more on their side which helps them to maintain such good flow. However, the system is still unsuitable for further development as most of the supply is done by the manufacturers. It does not encourage the different levels in the supply chain to get enhanced than their current condition. Supply Channel of Pharmaceutical Industry in Bangladesh As mentioned earlier in the introduction, most of the level of supply chain is owned by the manufacturers. Most of the pharmaceutical companies have their own distributors. Unlike the most, few companies like Novo Nordisk uses Transcom, the only distributing company in this sector, to deliver their product to the next level of supply chain. The figure 1 shows the supply channel of the industry. Each level of the channel is discussed below. Production: This is the level where the drugs are manufactured. At this level, drugs are kept open and ready to handover to the next level. Quarantined Warehouse: This is the level where product-quality is got checked. Also, to get the permission of market the product governmental approval is acquired here as well. After being tested here, taxes are paid and the products move to the next level. Central DPG Duty Paid Warehouse: After being tested the products are moved to Central DPG where they call it the â€Å"Finished Goods†. Then the goods are moved to Duty Paid Warehouse. Deports: Deports are very important level in the channel. These deports are established in different places in the country to meet the demands of a specific region. Depending on the sales average of recent past and the reports from the medical representatives and sales representatives, these deport stock goods which can fulfill on an average 10 days’ demand. Most of the big companies use SAP (System analysis and program development) software to make a database of the demands so that deports can store the goods accordingly. Medical/Sales Representative (MR SR): These are the agents, assigned by the manufacturing companies. They are responsible to gather information of demands for different drugs within a given area. They use devices that are connected with the main database. Through these devices they pass relevant information and invoices to regional deport. Till this level, the manufacturing companies own the intermediaries. Under the supervision of MR and SR, the goods are delivered through a pre-designed route to the different customers of these companies. Retail Drugstore: Retail drugstores are the most convenient places for the direct consumers of medicines. These retail shops get 2% discount on the medicines provided by the manufacturers. Wholesalers: Wholesalers take orders in bulk from the manufacturers and sell them to the retailers. The companies give 3% discount on the medicines for them. Potential Retailers: Big names of retail stores like Lazz Pharma get extra attention to the manufacturing companies. They also get 3% discount. Doctors: Many doctors have their own dispensary and they are one of the customers for the pharmaceutical companies. They get 3% discount as well. Hospital/Clinics: These places need more types of medicine than the others. For the medicines that need to be injected, they get up to 10% discount. Government/tender: These are special orders which happen occasionally. Delivery Company: The only distributing company in this sector at Bangladesh is Transcom which delivers drugs to different retail shops, hospitals etc after taking them from manufacturing company. International Distribution: Bangladeshi pharmaceutical companies export medicines mostly in Africa and the distribution is done by local distributing companies. Other Relevant Information: VAT(Value Added Tax) is added twice. The first time is done at the beginning of the production which 15%. After that 1. 5% VATable Amount is added. Finally, another 15% VAT is added on the trade price to retailers. Figure 1: The Supply Channel of Pharmaceutical Industry in Bangladesh Recent Trends in the Drugstore Channels of Other Countries Unlike Bangladesh, other countries have more competitive market for having intense competition in the levels of marketing channels. Most of the countries have different distribution system than Bangladesh. Even our neighbor country India has a different channel system in this field. As mentioned in the journal of Kellar and Langer (2008), the supply channel of drugs in India looks like figure 2. Figure 2: Current distribution chain in India In such system, manufacturing companies assign CFA(clearing and forwarding agents) who clears and forwards the medicines to stockists who are independent intermediaries. Through the stokists the drugs go to the consumers. In India, retail pharmacy chain is also introduced which is still unknown to us in Bangladesh. According to Kellar and Langer (2008), â€Å"The first retail Pharmacy chain was started by the Subiksha Retail Services Pvt Ltd. The Medicine Shoppe, one of the largest retail drug stores in the US, opened two retail outlets in Mumbai and has franchised three more in Mumbai, Calcutta, and Baroda. Others have also entered the field including Health Glow, Pills Powders, and Reliance that US and EU, the expenditure on SCM alone is perhaps 2%, whereas in India it averages 4–6% of total sales. Also, this multi-layered system got more improved as India adopts IT in this sector. In the United States, the market is hugely developed. They have introduced new technologies and innovations long before us. They are introducing new techniques and packaging system as well to make the product more user-friendly to deliver it to the consumers. As the different levels of supply channel adapt new enhancement every day, the competition arises. In the writing of Gabler (2005), he mentioned about new packaging and delivery system that was brought up by Target Corp. and PrairieStone Pharmacy of USA. Target Corp. developed a new bottle called ClearRx, flat-paneled bottles that fit larger-print labels, color-coded rings to distinguish medicine between family members and user-friendly liquid dispensers for administering medicine to children. On the other hand, PrairieStone Pharmacy took a different approach. According to Gabler (2005), â€Å"With Daily Dose, PrairieStone will package customers medications in individual pouches according to the time of day and day of the week it needs to be taken. For example, each packet in the 30-day supply is labeled Morning, Afternoon or Evening with Dinner. For USA, most of the intermediaries are independent. Intermediaries are so well-developed, the independent pharmacies find it very difficult to sustain in the market. In the writing of Lehman (2008), she mentioned about declining number of independent pharmacies in USA. In addition she mentioned Miami-Luken Inc which began buying independent pharmacies to as their customer base was comprised entirely of privately owned drugstores. In the writing, Lehman (2008) also described, â€Å"Miami-Luken cannot compete with supply-chain drugstores, such as Walgreens and CVS, because it could not handle the product demands. So guaranteeing its customer base of independents became a top priority. † USA also found it very important to use technologies for record keeping. Medicines are very sophisticated things to consume. And when it comes to a patient who is suffering from a disease that needs extra attention, a wrong medication could put the person in grave danger. Robertson (2008) mentioned in her writing about such incident for which California law announced to apply a electronic record for medicines in the supply chain. At 2004 such decision was taken for which it was required to keep record of medicines electronically at every steps from manufacture to retail. Comparison of Bangladesh with Other Countries Bangladeshi industry in this particular sector is still using a supply channel that was once practiced in developed countries a long time ago. For not having multi-layered supply channel, the industry is not being able to provide more developed delivery. The adaption of technology is still not taken by all the pharmaceutical companies. To improve the competition as well as the quality of supply, the industry needs drugstore chain and independent intermediaries like Transcom so that the manufacturer can concentrate more on developing the drugs and others can worry about the distribution. In this way, every level of supply channel would become self-efficient and well-developed. Innovation on the other hand will start to come as well. The probable trend of drugstore channel in Bangladesh is yet to be foreseen. As there is no indication of change in the current system, one cannot expect multi-layered supply channel in the near future. Moreover, the system has just started to developed. To become something like the other developed countries, it will take at least another decade. Conclusion To conclude, I would want to make a few suggestions regarding the development of supply chain of pharmaceutical industry in Bangladesh. This system needs to enhance with competition. The quality of drugs is good enough but the delivery system is not. Hence, more independent intermediaries should be encouraged to enter the market and thus make channel a competitive and developed one.

Tax Dollars Should Fund Religious Schools Essay -- Argumentative Persu

Tax Dollars Should Fund Religious Schools The issue of whether or not to use tax dollars to provide private schools with vouchers has been controversial for many years now.   Many people feel that it is our governments obligation to provide private institutions with the proper funds, while others believe that if private schools inherit our tax dollars then it is violation of our constitution as it promotes a particular religion.   I think it is our government's responsibility to provide each and every school with tax dollars, regardless of its orientation.   Many reasons, especially popularity and success rates provide substantial evidence that private schools should be funded by government vouchers. The main concern of those who oppose the use of government money for private schools is whether or not it would be constitutional.   In the past, many Supreme Court cases have proven that school vouchers for private schools are constitutional.   For example in Board of Education vs. Allen it was established that providing funds for private schools does not violate the Establishment C...

Kinetic

We can use many of Technique or methods for separating of compounds or mixtures .and we can by those methods studying of kinetic for reactions ,determine of reaction rate and reaction order . some of those methods are : mass spectrometric , spectrometric and Chromatographic Methods . But in this paper I just talk about chromatographic method . exactly, gas chromatography . Chromatography:Few methods of chemical analysis are truly specific to a particular analyte. It is often found that the analyte of interest must be separated from the myriad of individual compounds that may be present in a sample. As well as providing the analytical scientist with methods of separation, chromatographic techniques can also provide methods of analysis . Chromatography involves a sample (or sample extract) being dissolved in a mobile phase (which may be a gas, a liquid or a supercritical fluid). The mobile phase is then forced through an immobile, immiscible stationary phase. The phases are chosen such that components of the sample have differing solubility in each phase. A component which is quite soluble in the stationary phase will take longer to travel through it than a component which isn't very soluble in the stationary phase but very soluble in the mobile phase. As a result of these differences in mobilities , sample components will become separated from each other as they travel through the stationary phase. Gas chromatography methods that are used for studying first-order reaction kinetics by gas chromatography : (1) classical kinetic methods where samples of batch-wise kinetic studies are analyzed by enantioselective gas chromatography, (2) stopped-flow methods performed on one chiral column, (3) stopped-flow methods performed on an achiral column or empty capillary coupled in series with two chiral columns, (4) on-flow method performed on an achiral column coupled in series with two chiral columns, and (5) reaction gas chromatography, known as a dynamic gas chromatography. The following procedures have been developed to determination peak areas of reaction constituents in such complex chromatograms: (i) methods based on computer-assisted simulations of chromatograms where the kinetic activation parameters for the interconversion of enantiomers are obtained by iterative comparison of experimental and simulated chromatograms, (ii) stochastic methods based on the simulation of Gaussian distribution functions and using a time-dependent probability density function, (iii) approximation function and unified equation, (iv) computer-assisted peak deconvolution methods. Fast reaction :Reaction between metal carbonate and acid.- Reaction between calcium carbonate and hydrochloric acid :CaCO3 + 2HCl -; CaCl2 + H2O + CO2Reaction between reactive metal and water .-reaction between lithium and water :2Li + 2H2O -; 2LiOH + H2Combustion .-combustion of magnesium in oxygen .2Mg + O2 -; 2MgOPrecipitation (double decomposition )-precipitation of silver (I) chloride :AgNO3 + HCl -; AgCl + HNO3 Rate :The rate can be measured using apparatus on the rightrate of reaction = d[CaCl2] / t ,or d[CO2] / t or d[H2O] the rate can be decrease or increase with change of temperature , concentration , pressure , surface area or size of molecules .concentration : when the concentration is decrease the rate decrease .example : 3 g of calcium carbonate react with 5 g of hydrochloric acid to produce 3 g of carbon dioxide in 10s at 25C and 1atm. rate = -d [CaCO3] / t = -d[3] / 10 . But we decrease of concentration of calcium carbonate to 2 .rate = -d[2] / 10 .pressure and temperature : also when decrease the pressure or temperature the rate decrease .example : 3 g of calcium carbonate react with 5 g of hydrochloric acid to produce 3 g of carbon dioxide in 10s at 25C and 1atm. rate = -d [CaCO3] / t = -d[3] / 10s . but the time is increase to 20s , because the pressure decrease to 0.5 and temperature decrease to 15 , so the rate = -d [3] / 20s . In a chemical reaction the reactant decrease over time and product increase over time . The rate will decrease over time as the hydrochloric acid is used up (its concentration decreases)The graph in after page shows the volume of gas produced over time in the reaction between HCl and CaCO3 .All three reactions result in the same amount of CO2 gas being produced; however the higher the concentration of HCl, the faster the rate of reaction, thus the less time it takes for the reaction to be complete . The table below shows the time taken to produce 50cm3Â  of CO2Â  for each concentration of HCl :Rate of reaction / cm3 of CO2 s-1 Time take to produce 50 cm3 of CO2/1s Concentration of HCl /mold m-30.86 58 2.00.42 120 2.00,21 235 0.5 From the results in the table above, it can be worked out that the rate of reaction is directionally proportional to the concentration of hydrochloric acid, so if you halve the concentration of HCl will be halved, if you quarter the concentration, the rate will be quartered . rate = k [HCl]1 Order :The order of a reaction is not necessarily an integer. The following orders are possible :Zero: A zero order indicates that the concentration of that species does not affect the rate of a reaction .Negative integer: A negative order indicates that the concentration of that species INVERSELY affects the rate of a reaction .Positive integer: A positive order indicates that the concentration of that species DIRECTLY affects the rate of a reaction . Non-Integer: Non-integer orders, both positive and negative, represent more intricate relationships between concentrations and rate in more complex reactions.So, in The reaction of calcium carbonate with hydrochloric acid is said to be first order with respect to hydrochloric acid .This is because the rate depends upon the concentration of hydrochloric acid to the power one . Technique :we can measure of rate of carbon dioxide by gas chromatography , gas chromatography can separating of compound by boiling point , and you can analyze results on your computer and measuring of rate of CO2 .and you can determine of rate by flow reaction that may be is easer method .

The Book Brave New World - 1481 Words

Aws Aldajan Prof. Steven Schlesinger Philosophy 112 In the book Brave New World by Aldous Leonard Huxley, there are many topics covered about the world, freedom, and men. One of the topics discussed is the theory of evolution. There are many arguments presented about how the world and people evolved. There are different arguments created by creationists and evolutionists. For the creationists, everything is created by a creator such as God and that matter was formed by him to create the earth and even people on earth as well as other creatures in the universe. On the other hand, the evolutionists do not believe in creation, and they argue that everything evolved from their old forms to their new forms now. Another topic presented is the discussion about freedom which evolutionists believed not to exist since matter is not free and it is governed by laws of nature and that includes people and all living things and non-living things in the whole universe. 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